Perfusion-Independent Tissue Hypoxia in Cardiac Hypertrophy in Mice Measured by 64Cu-CTS PET Imaging
Friedrich Baark, Aidan M. Michaels, Edward C. T. Waters, Alex Rigby, Jana Kim, Zilin Yu, Victoria R. Pell, James Clark, Philip J. Blower, Thomas R. Eykyn, Richard Southworth
This study shows that 64Cu-CTS PET detects hypoxia in hypertrophic mouse hearts independent of perfusion, linking it to structural changes and metabolic shifts.
bioRxiv · Apr 22, 2024 · PreprintBioengineering