Sparse parallel independent component analysis and its application to identify linked genomic and gray matter alterations underlying working memory impairment in attention-deficit/hyperactivity disorder
Kuaikuai Duan, Jiayu Chen, Vince D. Calhoun, Wenhao Jiang, Kelly Rootes-Murdy, Gido Schoenmacker, Rogers F. Silva, Barbara Franke, Jan K. Buitelaar, Martine Hoogman, Jaap Oosterlaan, Pieter J Hoekstra, Dirk Heslenfeld, Catharina A Hartman, Emma Sprooten, , Jingyu Liu
This paper introduces spICA to link genomic and brain imaging data, identifying a SNP and GMV association in ADHD linked to working memory deficits.
bioRxiv · Jul 11, 2020 · PreprintBioengineering