Noninvasive focal gene transfer of chemogenetic proteins in the primate brain
Michael R. Corigliano, T. Vincenza Parks, Simeon S. Guretse, Leila Letica, Isabela Zimmermann Rollin, Sarah K. A. Pell, Vinicius P. Campos, Diego Szczupak, David J. Schaeffer
This study demonstrates noninvasive delivery of chemogenetic proteins to the primate brain using focused ultrasound, enabling activation of long-range frontal cortex circuits without surgery.
Cell Reports Methods · May 4, 2026Peer-reviewedNeuroscience