David J. Schaeffer

This paper demonstrates noninvasive, focal gene delivery to the primate spinal cord using focused ultrasound, showing functional transgene expression and preserved neurological function.

The paper develops a hierarchical atlas for gray-matter parcellation across multiple species, validated through cross-species comparisons and connectivity analysis.

This study demonstrates noninvasive delivery of chemogenetic proteins to the primate brain using focused ultrasound, enabling activation of long-range frontal cortex circuits without surgery.

This paper describes a new neural implant that enables long-term, aseptic recording of both neurochemical and electrophysiological activity in nonhuman primates.

This paper introduces SpIC3D, a 3D imaging method for high-resolution visualization of spinal structures, enabling quantification of neuronal density and volumetric reconstruction for computational modeling.

The paper provides open-access CAD files and software for marmoset neuroscience apparatus, reducing the need for individual lab development.

The paper introduces an open-source, 3D-printable MRI-compatible stereotaxic frame for nonhuman primates, enabling accurate multimodal presurgical mapping and deep-brain interventions.

This paper demonstrates noninvasive delivery of AAV vectors to the marmoset brain using tFUS and BBB opening, enabling focal neuronal tracing.

The paper identifies thalamic commissures in primates, showing they connect cortex to contralateral thalamus and exist in both healthy and malformed human brains.

This study demonstrates non-invasive blood-brain barrier disruption in marmosets using transcranial focused ultrasound with microbubbles, establishing safe and reliable parameters for preclinical applications.

This paper introduces a method to simultaneously measure whole-brain activation in two socially interacting marmoset monkeys using functional MRI and finds neuronal synchrony in brain regions involved in social processing.

This study investigates the functional organization of frontoparietal networks in marmosets using resting-state fMRI, finding patterns similar to macaques.

This study uses movie-driven fMRI to identify whole-brain functional correspondences between marmosets and humans, finding conserved higher-order visual areas but species-specific responses to animal faces.

This study examines how ketamine affects gaze patterns during face viewing in marmosets, finding disrupted scan paths but limited motor control effects.

This study examines structural white matter changes in macaques after prefrontal cortex lesions and finds that recovery is associated with changes in fractional anisotropy in specific fiber tracts.

This paper maps somatosensory responses in awake marmosets using fMRI, finding body representations in cortical and subcortical regions similar to Old World primates and humans.

This study compares cortico-subcortical functional connectivity in marmosets and humans using resting-state fMRI, finding both similarities and species-specific differences in network patterns.

This study identifies face-selective patches in the frontal cortex of marmosets, suggesting a conserved neural network for social face processing across primate lineages.

The paper uses fMRI in awake marmosets to identify brain networks activated by looming and receding visual stimuli, finding distinct patterns associated with looming that may support protective behaviors.

This study identifies the frontal eye field in marmosets using microstimulation, showing homology with macaques and supporting marmosets as a model for FEF research.

The paper describes methods for restraining and training common marmosets to perform oculomotor tasks, demonstrating their suitability for neurophysiological studies.