Noninvasive Focal Gene Delivery of Functional Neural Actuators to the Primate Spinal Cord using Focused Ultrasound
Michael R. Corigliano, Simeon S. Guretse, Natasha Toussaint Nosenchuck, Isabela Zimmermann Rollin, Leila Letica, Diego Szczupak, Vinícius P. Campos, Lucy Liang, Myung‐chul Noh, T. Kevin Hitchens, Elvira Pirondini, Rebecca P. Seal, M. K. Lin, David J. Schaeffer
This paper demonstrates noninvasive, focal gene delivery to the primate spinal cord using focused ultrasound, showing functional transgene expression and preserved neurological function.
bioRxiv · Sep 12, 2026 · PreprintNeuroscience