Minute- and second-scale hippocampal network dysfunctions in the 3xTgAD mouse model of Alzheimer's disease are prevented by TSPO knockout
Benjamin Vidal, Aurélien M. Badina, Violina Dorogan, Gabriel Henrique Schirmbeck, Eduardo Farias Sanches, Kelly Ceyzériat, Marit S. Knoop, Laurene Abjean, Stergios Tsartsalis, Stéphane Vladimir Sizonenko, Olivier Baud, P. Millet, Valerio Zerbi, Benjamin B. Tournier
This study shows that TSPO knockout prevents hippocampal network dysfunctions in 3xTgAD mice without affecting amyloid or tau levels.
Journal of Cerebral Blood Flow & Metabolism · Jun 1, 2026Peer-reviewedNeuroscience