Kelly Ceyzériat

The paper uses spatial transcriptomics and proteomics to show that Alzheimer's disease inflammation peaks in white matter, driven by lipid and carbonyl stress, and is linked to cognitive decline.

This study shows that TSPO knockout prevents hippocampal network dysfunctions in 3xTgAD mice without affecting amyloid or tau levels.

This study shows that oxytocin release reduces acute neuroinflammation and improves long-term brain development after pediatric traumatic brain injury in mice.

The paper examines microglial, inflammatory, and oligodendrocyte dynamics in Alzheimer's disease stages, finding early neuroinflammation impairs oligodendrocytes while late stages show partial recovery.

This study investigates the effects of repeated low-intensity focused ultrasound (LiFUS) with microbubbles on microglial profiles in a rat model of Alzheimer's disease, finding both short-term and long-term changes in inflammation and amyloid levels.

This study investigates how hippocampal AD pathology affects striatal dopamine release and locomotion through chemogenetic manipulation in AD rat models.

This study identifies cell type-specific immune alterations in bipolar disorder brains, showing reduced proinflammatory microglia and metabolic/immune dysregulation in astrocytes.

The paper shows TSPO expression increases in activated microglia in rodent models but not in human neurodegenerative diseases, indicating species-specific differences in TSPO function.

This study investigates the role of reactive astrocytes in Alzheimer's disease by modulating the JAK2-STAT3 pathway in 3xTg-AD mice, finding no effect on Tau or amyloid pathology but behavioral changes.