Elucidating design principles for Ribozyme-Enabled Tissue Specificity (RETS) to allow precise expression without specialized promoters.
Max M. Combest, Josh Conlin, Vivia Van De Mark, Morgan Boisen, Hadley Colwell, Arjun Khakhar
This paper introduces RETS, a method for tissue-specific transgene expression in plants using ribozymes, and demonstrates its application in Arabidopsis thaliana for biosensors and phenotypic engineering.
bioRxiv · Aug 14, 2025 · PreprintSynthetic Biology