Pan-repository analysis reveals a drug-activating function of microbial bile acid conjugation
Vincent Charron‐Lamoureux, Patricia E. Kelly, Simone Zuffa, Abubaker Patan, Marta Sala‐Climent, Corinn Walker, Haoqi Nina Zhao, Shipei Xing, Harsha Gouda, Julius Agongo, Erin R. Reilly, Lina Sallam, Selene F. H. Shore, Subhomitra Ghoshal, Anika K Harpavat, , Pieter C. Dorrestein
The paper identifies microbial bile acid conjugation as a drug-activating function for 5-ASA, revealing its therapeutic relevance through metabolomics analysis.
bioRxiv · Mar 4, 2026 · PreprintBiochemistry