Cancer BiologybioRxivPreprint
Lineage Recording Reveals the Phylodynamics, Plasticity and Paths of Tumor Evolution
D. Yang, M. G. Jones, S. Naranjo…·J. S. Weissman
The paper tracks tumor evolution in a mouse model using lineage tracing and single-cell RNA-seq, revealing plasticity, fitness-associated programs, and stereotypical evolutionary trajectories.