C. S. McGinnis

This paper uses longitudinal scRNA-seq to study immune changes in lung metastasis, identifying inflammatory programs and signaling networks associated with metastatic progression.

This study analyzes single-cell transcriptomes of primary tumors and metastases from breast cancer models, identifying transcriptional differences and gene signatures linked to metastatic potential and patient outcomes.

The paper tracks tumor evolution in a mouse model using lineage tracing and single-cell RNA-seq, revealing plasticity, fitness-associated programs, and stereotypical evolutionary trajectories.