W. C. Warren

Single cell sequencing of pig lungs reveals immune responses underlying influenza infection and oseltamivir therapy

This study uses single-cell sequencing to analyze pig lung immune responses to influenza infection and oseltamivir treatment, identifying conserved and species-specific features.

Patient-derived tumor organoids from resected non-small cell lung cancers for high-throughput response testing with approved and repurposed drugs

This study develops patient-derived tumor organoids from non-metastatic NSCLC tumors to test drug responses and identify chemoresistance mechanisms, finding 50% of organoids were chemo-resistant and could be sensitized by repurposed drugs.

A novel fishing cat reference genome for the evaluation of potential germline risk variants

This paper presents a fishing cat reference genome to evaluate germline risk variants for transitional cell carcinoma, identifying BRCA2 mutations associated with the disease.

Patterns of lineage-specific genome evolution in the brood parasitic black-headed duck (Heteronetta atricapilla)

The paper generates high-quality genomes of the black-headed duck and related species to study lineage-specific evolutionary changes associated with brood parasitism.

Genome assemblies across the diverse evolutionary spectrum of Leishmania protozoan parasites

The paper provides high-quality genome assemblies and gene annotations for 13 Leishmania and related species to study the origins of parasitism.

Concurrent invasions by European starlings (Sturnus vulgaris) suggest selection on shared genomic regions even after genetic bottlenecks

The paper compares whole-genome sequences of European Starlings from native and introduced populations to show that post-bottleneck expansion supports local adaptation through selection on shared genomic regions.

The developmental and genetic architecture of the sexually selected male ornament of swordtails

The paper identifies genes associated with sword development in swordtail fish by analyzing transcriptional profiles and genetic mapping.

The role of gene flow in rapid and repeated evolution of cave related traits in Mexican tetra, Astyanax mexicanus

This study shows that gene flow plays a significant role in the rapid evolution of cave-related traits in Mexican tetra, challenging the classic hypothesis of disuse and drift.