Author

E. Maldonado

St. Jude Children's Research Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 3 Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:zebrafish· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:statistical model· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Organism:E. coli· 1

Frequent Co-Authors

N. Rohner· 3 shared A. Kenzior· 2 shared R. Peuss· 2 shared A. C. Box· 1 shared A. C. Keene· 1 shared A. Gluesenkamp· 1 shared A. Herman· 1 shared A. T. Banaszak· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersEvolutionary Biology

N. Rohner

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Purification of post-transcriptionally modified tRNAs for enhanced cell-free translation systems

Evan M. Kalb, Jose L Alejo, Leticia Dias-Fields, Isaac J. Knudson, Joshua A. Davisson, E. Maldonado, Kanokporn Chattrakun, Shangsi Lin, Jung Yeon Lee, Tianchen He, Alanna Schepartz, Shenglong Zhang, Scott C. Blanchard, Aaron E. Engelhart, Katarzyna P. Adamala

This paper develops a method to purify post-transcriptionally modified tRNAs from E. coli, enhancing translation yields and fidelity in cell-free systems.

Nucleic Acids Research · Feb 24, 2026Peer-reviewedBiochemistry

Metabolic reprogramming underlies cavefish muscular endurance despite loss of muscle mass and contractility

L. Olsen, M. Levy, J. K. Medley, H. Hassan, R. Alexander, E. Wilcock, K. Yi, L. Florens, S. McKinney, R. Peuss, J. Persons, A. Kenzior, E. Maldonado, A. Gluesenkamp, E. Mager, , N. Rohner

This paper shows cavefish have reduced muscle mass and contractility but increased muscular endurance due to metabolic reprogramming involving glycogen utilization.

bioRxiv · Mar 12, 2022Evolutionary Biology

Discovery and characterization of Hv1-type proton channels in reef-building corals.

G. Rangel-Tescas, C. Cervantes, M. A. Cervantes-Rocha, E. Suarez-Delgado, A. T. Banaszak, E. Maldonado, I. S. Ramsey, T. Rosenbaum, L. D. Islas

This study identifies and characterizes Hv1-type proton channels in reef-building corals, revealing their biophysical properties and developing an allosteric gating model.

bioRxiv · Apr 8, 2021Biophysics

Adaptation to low parasite abundance affects immune investment strategy and immunopathological responses of cavefish

R. Peuss, A. C. Box, S. Chen, Y. Wang, D. Tsuchiya, J. L. Persons, A. Kenzior, E. Maldonado, J. Krishnan, J. P. Scharsack, B. P. Slaughter, N. Rohner

This study shows that cavefish, adapted to low parasite abundance, have a more sensitive immune system with reduced proinflammatory responses and shifted immune investment to adaptive immunity.

bioRxiv · Dec 18, 2019Evolutionary Biology

The role of gene flow in rapid and repeated evolution of cave related traits in Mexican tetra, Astyanax mexicanus

A. Herman, Y. Brandvain, J. Weagley, W. R. Jeffery, A. C. Keene, T. J. Y. Kono, H. Bilandzija, R. Borowsky, L. Espinasa, K. O'Quin, C. P. Ornelas-Garcia, M. Yoshizawa, B. Carlson, E. Maldonado, J. B. Gross, , S. E. McGaugh

This study shows that gene flow plays a significant role in the rapid evolution of cave-related traits in Mexican tetra, challenging the classic hypothesis of disuse and drift.

bioRxiv · May 31, 2018Evolutionary Biology