Reactive oxygen species accelerate de novo acquisition of antibiotic resistance in E. coli
W. Qi, M. J. Jonker, W. de Leeuw, S. Brul, B. H. Ter Kuile
This study shows that reactive oxygen species from sublethal antibiotics promote de novo resistance in E. coli by increasing DNA damage and mutation rates.
bioRxiv · Jul 21, 2023 · PreprintMicrobiology