Single-molecule Imaging of SWI/SNF Chromatin Remodelers Reveal Multi-modal and Cancer-mutant-specific Landscape of DNA-binding Dynamics
W. Engl, S. Hendrik, A. Kunstar-Thomas, S. Chen, W. S. Ng, Z. W. ZHAO
This paper uses single-molecule imaging to analyze the dynamics of SWI/SNF chromatin remodelers in live cells, revealing mutant-specific changes in binding behavior linked to cancer.
bioRxiv · Jul 28, 2023 · PreprintBiophysics