Author

W. H. Chan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1

Frequent Co-Authors

A. M. Kane· 1 shared B. A. Leggett· 1 shared B. Salik· 1 shared C. E. Bond· 1 shared C. J. Wright· 1 shared C. Su· 1 shared D. M. McKeone· 1 shared D. Micati· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCancer Biology

A. M. Kane

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

A DNA condensation code for linker histones

M. Watson, D. Sabirova, M. C. Hardy, Y. Pan, H. Yates, C. J. Wright, W. H. Chan, E. Destan, K. Stott

This study develops an in-vitro model to investigate how linker histone C-terminal tails influence chromatin condensation states through charge density, lysine/arginine ratio, and proline-free regions.

bioRxiv · Nov 20, 2023 · PreprintBiophysics

Aspirin synergizes with regorafenib to reduce growth of colorectal cancer

C. Su, L. J. Fennell, C. E. Bond, A. M. Kane, G. Kerr, T. Jarde, D. Micati, R. M. Engel, W. H. Chan, S. Hlavca, S. Archer, P. J. McMurrick, H. Hammerlindl, F. Lim, B. Salik, , V. L. Whitehall

This study shows that aspirin and regorafenib together reduce colorectal cancer growth in preclinical models by inhibiting the PI3K-Akt-mTOR pathway and activating AMPK.

bioRxiv · Feb 11, 2022 · PreprintCancer Biology