Author

G. Kerr

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Animal Behavior & Cognition· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

H. E. Abud· 2 shared A. Buhles· 1 shared A. De Paoli· 1 shared A. M. Kane· 1 shared A. Mansell· 1 shared A. Weiss· 1 shared B. A. Croker· 1 shared B. A. Leggett· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCancer Biology

H. E. Abud

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Author profile →

4 papers

Recent·Most cited

Alpha-synuclein pre-formed fibrils injected into prefrontal cortex primarily spread to cortical and subcortical structures and lead to isolated behavioral symptoms

M. A. Weber, G. Kerr, R. Thangavel, M. M. Conlon, H. A. Abdelmotilib, O. Halhouli, Q. Zhang, J. C. Geerling, N. S. Narayanan, G. M. Aldridge

This study injects alpha-synuclein pre-formed fibrils into the prefrontal cortex of mice, showing spread to cortical and subcortical regions and mild behavioral changes.

bioRxiv · Jan 31, 2023Animal Behavior & Cognition

Aspirin synergizes with regorafenib to reduce growth of colorectal cancer

C. Su, L. J. Fennell, C. E. Bond, A. M. Kane, G. Kerr, T. Jarde, D. Micati, R. M. Engel, W. H. Chan, S. Hlavca, S. Archer, P. J. McMurrick, H. Hammerlindl, F. Lim, B. Salik, , V. L. Whitehall

This study shows that aspirin and regorafenib together reduce colorectal cancer growth in preclinical models by inhibiting the PI3K-Akt-mTOR pathway and activating AMPK.

bioRxiv · Feb 11, 2022 · PreprintCancer Biology

Therapeutic assessment of targeting ASNS combined with L-Asparaginase treatment in solid tumors and investigation of resistance mechanisms

V. Apfel, D. Begue, V. Cordo, L. Holzer, L. Martinuzzi, A. Buhles, G. Kerr, I. Barbosa, U. Naumann, M. Piquet, D. Ruddy, A. Weiss, S. Ferretti, R. Almeida, D. Bonenfant, , G. G. Galli

This study assesses targeting ASNS with L-Asparaginase in solid tumors, identifies resistance mechanisms, and proposes therapeutic combinations.

bioRxiv · Sep 8, 2020Cancer Biology

NOD1 mediates non-canonical inflammasome processing of interleukin-18 in epithelial cells to Helicobacter pylori infection.

L. S. Tran, L. Ying, K. D'Costa, G. Wray-McCann, G. Kerr, L. Le, C. C. Allison, J. Ferrand, H. Chaudhry, J. Emery, A. De Paoli, S. Creed, M. Kaparakis-Liaskos, J. Como, J. Dowling, , R. L. Ferrero

This study identifies NOD1 as a key regulator of IL-18 processing in epithelial cells during Helicobacter pylori infection, independent of canonical inflammasome proteins.

bioRxiv · Mar 24, 2019 · PreprintImmunology