ImmunologybioRxiv
Modulation of MHC-E transport by viral decoy ligands is required for RhCMV/SIV vaccine efficacy
M. Verweij, S. G. Hansen, R. Iyer…·K. Früh
This study shows that the Rh67/UL40 protein in RhCMV/SIV vectors is necessary for MHC-E-restricted CD8+ T cell responses and SIV protection in rhesus macaques.
DOI 10.1126/science.abe9233