Author

W. J. Fitzsimmons

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 4

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Approach:statistical model· 3 Assay:whole-genome sequencing· 3 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:phylogenetics / evolution· 1

Frequent Co-Authors

A. S. Lauring· 4 shared A. L. Valesano· 3 shared E. T. Martin· 3 shared J. G. Petrie· 2 shared K. E. Rumfelt· 2 shared A. Monto· 1 shared A. S. Monto· 1 shared C. N. Blair· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersMicrobiology

A. S. Lauring

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A rapid and flexible microneutralization assay for serological assessment of influenza viruses

K. E. Rumfelt, W. J. Fitzsimmons, R. Truscon, A. Monto, E. T. Martin, A. S. Lauring

The paper introduces a luciferase-based microneutralization assay (LMN) that correlates with HAI titers and can detect antigenic differences between egg-adapted and cell-derived influenza strains.

bioRxiv · Feb 2, 2023Microbiology

Temporal dynamics of SARS-CoV-2 mutation accumulation within and across infected hosts

A. L. Valesano, K. E. Rumfelt, D. E. Dimcheff, C. N. Blair, W. J. Fitzsimmons, J. G. Petrie, E. T. Martin, A. S. Lauring

This study analyzes SARS-CoV-2 mutation accumulation within and across infected hosts, finding low intrahost diversity and limited shared variants between unrelated individuals.

bioRxiv · Jan 19, 2021Microbiology

The early evolution of oral poliovirus vaccine is shaped by strong positive selection and tight transmission bottlenecks

A. L. Valesano, M. Taniuchi, W. J. Fitzsimmons, M. O. Islam, T. Ahmed, K. Zaman, R. Haque, W. Wong, M. Famulare, A. S. Lauring

This study uses high-depth genome sequencing to analyze the early evolution of monovalent OPV2 in vaccinated individuals and their contacts, revealing strong positive selection and tight transmission bottlenecks.

bioRxiv · Aug 20, 2020Microbiology

Influenza B viruses exhibit lower within-host diversity than influenza A viruses in human hosts

A. L. Valesano, W. J. Fitzsimmons, J. T. McCrone, J. G. Petrie, A. S. Monto, E. T. Martin, A. S. Lauring

This study compares within-host genetic diversity between influenza B and A viruses, finding lower diversity in B viruses and a tight transmission bottleneck.

bioRxiv · Oct 2, 2019Microbiology