The Connexin 43 Carboxyl Terminal Mimetic Peptide alphaCT1 Prompts Differentiation of a Collagen Scar Matrix Resembling Unwounded Skin
J. Montgomery, W. J. Richardson, J. M. Rhett, F. Bustos, K. Degen, G. Ghatnekar, C. L. Grek, S. Marsh, L. J. Jourdan, J. W. Holmes, R. G. Gourdie
The paper investigates the effect of αCT1 peptide on scar matrix structure in human and animal models, finding that it reduces collagen fiber alignment and promotes a scar resembling unwounded skin.
bioRxiv · Jul 7, 2020Cell Biology