Author

W. L. Carroll

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Tsirigos· 1 shared H. Mulder· 1 shared J. Easton· 1 shared J. Pierro· 1 shared J. Saliba· 1 shared M. L. Loh· 1 shared N. Evensen· 1 shared P. A. Brown· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. Tsirigos

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1 paper

Recent·Most cited

NSD2 E1099K drives relapse in pediatric acute lymphoblastic leukemia by disrupting 3D chromatin organization

S. Narang, N. Evensen, J. Saliba, J. Pierro, M. L. Loh, P. A. Brown, H. Mulder, Y. Shao, J. Easton, X. Ma, A. Tsirigos, W. L. Carroll

This study shows NSD2 E1099K mutation disrupts 3D chromatin organization in B-ALL, leading to drug resistance and clonal evolution through compartmentalization changes.

bioRxiv · Feb 24, 2022 · PreprintCancer Biology