CRISPR screen reveals that EHEC’s T3SS and Shiga toxin rely on shared host factors for infection
A. R. Pacheco, J. E. Lazarus, B. Sit, S. Schmieder, W. Lencer, C. J. Blondel, J. Doench, B. M. Davis, M. K. Waldor
The paper uses a CRISPR screen to identify host factors critical for EHEC infection, finding shared dependencies between T3SS and Shiga toxin.
bioRxiv · May 8, 2018Microbiology