B. M. Davis

The T766M-EGFR lung cancer mutation promotes tumor growth by exploiting newfound assembly mechanisms in ligand-free EGFR oligomers

This study identifies how the T766M-EGFR mutation promotes tumor growth by utilizing new oligomer assembly mechanisms in ligand-free EGFR.

Abnormal enteric nervous system and motor activity in the ganglionic proximal bowel of Hirschsprung's disease

This study identifies abnormal ENS activity in HSCR mouse models, linking it to post-surgical motor dysfunction and suggesting functional ENS defects beyond aganglionosis.

A New Suite of Allelic Exchange Vectors for the Scarless Modification of Proteobacterial Genomes

The paper introduces pTOX vectors for scarless allelic exchange in Proteobacteria, enabling efficient gene modification and antibiotic resistance studies.

A Vibrio cholerae BolA-like protein is required for proper cell shape and cell envelope integrity

This study identifies IbaG, a BolA-like protein in V. cholerae, as critical for cell shape and envelope integrity through its role in iron-sulfur cluster protein biogenesis.

Transposon-insertion sequencing screens unveil requirements for EHEC growth and intestinal colonization

This study uses transposon-insertion sequencing to identify genes required for EHEC growth in vitro and in vivo, revealing new factors critical for intestinal colonization.

CRISPR screen reveals that EHEC’s T3SS and Shiga toxin rely on shared host factors for infection

The paper uses a CRISPR screen to identify host factors critical for EHEC infection, finding shared dependencies between T3SS and Shiga toxin.