Author

W. Nicholas Haining

Arsenal Biosciences (United States)ORCID 0000-0001-7871-3762Unclaimed ORCID profile · follow to get notified of new preprints

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W. Nicholas Haining2 papers

Biology Disciplines

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Bioinformatics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Assay:scRNA-seq· 2 Research Focus:benchmarking· 1 Approach:contrastive learning· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Research Focus:perturbation response prediction· 1 Research Focus:software / tool· 1

Frequent Co-Authors

Aaron R. CooperiD· 1 shared Adam Barner· 1 shared Alex Bastian· 1 shared Allyson J. MerrelliD· 1 shared Amaro N Taylor-WeineriD· 1 shared Amy Y. HuangiD· 1 shared Andrea Fua· 1 shared Andrew Cardozo· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBioinformatics

Aaron R. CooperORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintFeb 8, 2026

Harnessing Inflammatory Monocytes to Overcome Resistance to Anti-PD-1 Immunotherapy

Matthew P. Zimmerman, Amy Y. Huang, Emily K. Cox…·Brian C. Miller

This study shows CD40 agonist therapy reduces tumor growth in antigen presentation-deficient tumors by reprogramming monocytes and requiring IFN-gamma and CD8+ T cells for efficacy.

DOI 10.64898/2026.02.05.704029

𝕏 PostBluesky

BioinformaticsbioRxivPreprintDec 19, 2025

DINOcell: Learning Generalizable Perturbation Effects through Self-Distillation

Jonathan Li, Nilgun Tasdemir, Sofia Kyriazopoulou-Panagiotopoulou…·Amaro N Taylor-Weiner

DINOcell predicts cellular responses to perturbations using self-distillation in single-cell transcriptomics, outperforming baselines for single and combination gene effects.

DOI 10.64898/2025.12.16.694747

scRNA-seqdeep learning

𝕏 PostBluesky