Synchronization Temperature Determines the Location of RSV Fusion During Entry in Cultured Cells
C. C. Cadena-Cruz, M. C. De-Avila-Arias, H. M. Costello, L. V. Hurtado-Gomez, W. Martinez-De-La-Rosa, G. C. Macchia-Ceballos, W. Rosales-Rada, G. C. Valencia-Villa, P. C. Villalba-Amaris, M. Naeimi Kararoudi, M. E. Peeples, H. G. San Juan Vergara
This study shows that RSV fusion occurs at the plasma membrane when cells are warmed to 37°C from 22°C, but at the endosome when warmed from 4°C, suggesting the latter is an experimental artifact.
bioRxiv · Mar 9, 2021 · PreprintMicrobiology