Author

W. S. Harmsen

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Immunology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

A. Feven· 1 shared A. S. Mansfield· 1 shared D. Owen· 1 shared E. R. Dellacecca· 1 shared F. Lucien· 1 shared G. DeFranco· 1 shared H. Dong· 1 shared H. Zeng· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

A. Feven

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1 paper

Recent·Most cited

ImmunologybioRxivPreprintNov 25, 2022

Resilient CD8+ T cells maintain a high cytotoxic capacity by balancing ROS via ME1 upregulation

J. K. Gicobi, Z. Mao, G. DeFranco…·H. Dong

This paper identifies CX3CR1+ CD8+ T cells with low mitochondrial membrane potential as functionally resilient, showing high cytotoxicity and reduced ROS through ME1 upregulation, which enhances their anti-tumor activity.

DOI 10.1101/2022.11.25.517988

humanbulk RNA-seq

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