Emergence of distinct and heterogeneous strains of amyloid beta as Alzheimer s disease progresses in Down syndrome
A. M. Maxwell, P. Yuan, B. M. Rivera, W. Schaaf, M. Mladinov, V. P. Prasher, A. C. Robinson, W. F. DeGrado, C. Condello
This study identifies distinct and heterogeneous amyloid beta strains in Down syndrome patients with advanced Alzheimer's disease, suggesting unique pathogenic mechanisms compared to sporadic Alzheimer's.
bioRxiv · Jul 30, 2021Pathology