Active Gαi/o mutants accelerate breast tumor metastasis via the c-Src pathway
C. Lyu, A. K. Bhimani, W. T. Draus, R. Weigel, S. Chen
This study shows that active Gαi/o mutants enhance breast cancer metastasis via the c-Src pathway without affecting primary tumor growth.
bioRxiv · Jan 16, 2023 · PreprintCancer Biology