FOXK2 amplification and overexpression promotes breast cancer development and chemoresistance
Y. Yu, W.-M. Cao, F. Cheng, Z. Shi, L. Han, J.-L. Yi, E. M. da Silva, H. Dopeso, H. Chen, J. Yang, X. Wang, C. Zhang, H. Zhang
This study identifies FOXK2 amplification and overexpression in breast cancer, showing its role in promoting tumor growth, chemoresistance, and synergistic therapeutic responses when targeted with PI3KCA inhibitors.
bioRxiv · May 28, 2023 · PreprintCancer Biology