W.-S. Sun

PrgE: an OB-fold protein from plasmid pCF10 with striking differences to prototypical bacterial SSBs

The paper characterizes PrgE, a non-essential SSB from plasmid pCF10, showing it binds both single- and double-stranded DNA with unique quaternary assembly and DNA-binding properties.

Breaking Barriers: pCF10 Type 4 Secretion System relies on a self-regulating muramidase to modulate the cell wall

The paper reports the structure and function of PrgK, a component of the T4SS in pCF10, revealing its muramidase activity and self-regulating domains.

Structural foundation for the role of enterococcal PrgB in conjugation, biofilm formation and virulence

The paper reports the structure of PrgB from Enterococcus faecalis and shows how specific domains affect conjugation, biofilm formation, and virulence.

Structure of the enterococcal T4SS protein PrgL reveals unique dimerization interface in the VirB8 protein family

The paper determines the structure of the enterococcal T4SS protein PrgL, revealing a unique dimerization interface compared to other VirB8-like proteins.

Enterococcal PrgA extends far outside the cell and provides surface exclusion to protect against unwanted conjugation

This paper reports the structure and function of Enterococcus faecalis PrgA, showing it extends outside the cell to provide surface exclusion and reduce plasmid uptake.