New Gain-of-Function Mutations Prioritize Mechanisms of HER2 Activation
Christopher J. Giacoletto, Liz J. Valente, Lancer Brown, Sara E. Patterson, Rewatee H. Gokhale, Susan M. Mockus, Wayne W. Grody, Hong‐Wen Deng, Jerome I. Rotter, Martin R. Schiller
The paper identifies new gain-of-function HER2 mutations using a high-throughput assay and links them to improved patient survival.
medRxiv · Mar 3, 2025 · PreprintGenetic & Genomic Medicine