DOA/CLK2 phosphorylates Fl(2)d/WTAP to enhance m6A mRNA methyltransferase complex activity
David W. J. McQuarrie, Wei Bian, Matthias Soller
The paper identifies DOA/CLK2 as a kinase that phosphorylates Fl(2)d/WTAP to enhance m6A methyltransferase complex activity, crucial for dosage compensation and splicing regulation.
bioRxiv · Nov 25, 2024 · PreprintGenetics