LARP1-DM15/Sgt is a reader for cap-adjacent 2`-O-ribose methylation in TOP ribosomal protein mRNAs required for localization to synapses
Yuan W. Tian, Yavor Hadzhiev, Giancarlo Abis…·Matthias Soller
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University of ManchesterORCID 0000-0003-3844-0258Unclaimed ORCID profile · follow to get notified of new preprints
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16 papers
Recent·Most cited
Yuan W. Tian, Yavor Hadzhiev, Giancarlo Abis…·Matthias Soller
Deepanshu ND Singh, Matthias Soller
The paper identifies a role for Dpp/BMP signaling in specifying neuronal connectivity in Drosophila SPRINz neurons for post-mating behaviors through sexual differentiation.
Eileen Clemens, Sarah Brivio, Mohammed Al-Khafaji…·Jonathan Pettitt
The paper investigates the role of cap-adjacent 2'-O-ribose methylation (cOMe) in C. elegans, showing it protects transcripts from decapping exonuclease EOL-1 and is essential for growth and germline development.
Mohanakarthik Ponnadai Nallasivan, Deepanshu ND Singh, Mohammed Syahir RS Saleh, Matthias Soller
The paper identifies SP-target neurons in Drosophila that regulate post-mating behaviors through distinct neural circuits.
David W. J. McQuarrie, Frannie H. S. Stephens, Alexander D Ferguson…·Matthias Soller
The paper investigates rapid promoter evolution and expression divergence of male accessory gland genes in closely related Drosophila species, showing cis-regulatory changes drive expression differences.
Anna Lassota, James J. L. Hodge, Matthias Soller
The paper investigates species-specific neonicotinoid toxicity by engineering a cross-species chimeric nAChR subunit in Drosophila and assesses its impact on motor function and survival.
Florian D. Hastert, Jasmin Weber, Christina Bauer…·Maria Arroyo
This study shows TET dioxygenases localize at splicing speckles and promote RNA splicing through interactions with splicing factors and cytosine modifications.
Anna Lassota, Thomas C. Dix, Deepanshu N. D. Singh, Matthias Soller
The paper investigates stochastic and deterministic mechanisms of Dscam alternative exon inclusion in Drosophila and honey bees, revealing experience-directed splicing patterns.
David W. J. McQuarrie, Wei Bian, Matthias Soller
The paper identifies DOA/CLK2 as a kinase that phosphorylates Fl(2)d/WTAP to enhance m6A methyltransferase complex activity, crucial for dosage compensation and splicing regulation.
Pınar Ustaoğlu, David W. J. McQuarrie, Anthony Rochet…·Matthias Soller
This study shows that reducing Dscam expression enhances memory retention in honey bees and alters its alternative splicing during memory consolidation.
Irmgard U. Haussmann, Thomas C. Dix, David W. J. McQuarrie…·Matthias Soller
The paper develops PlatinumCRISPr, a tool for selecting efficient sgRNAs for CRISPR-Cas9 genome editing, identifies design constraints, and reports unintended DNA insertions from deletions.
Irmgard U. Haussmann, Yanying Wu, Mohanakarthik Ponnadai Nallasivan…·Matthias Soller
This study identifies CMTr1 and CMTr2 as cap-adjacent 2'-O-ribose methyltransferases essential for reward learning and synaptic mRNA localization in Drosophila.
Antonio Torres-Méndez, Sînziana Pop, Sophie Bonnal…·Manuel Irimia
The paper identifies a splicing program in neurons of Drosophila and mammals, showing how it evolves independently in different species to regulate ion channels and neuronal activity.
Mohanakarthik Ponnadai Nallasivan, Irmgard U. Haussmann, Alberto Civetta, Matthias Soller
This study identifies Nup54's role in Drosophila female reproductive behaviors by linking it to neuronal wiring and sexual differentiation in response to male sex-peptide.
Pınar Ustaoğlu, Jatinder Kaur Gill, Nicolas Doubovetzky…·Matthias Soller
This study shows that ELAV, a single elav gene in honey bees, is dynamically expressed and required for learning and memory through alternative splicing and subcellular localization changes.
Pınar Ustaoğlu, Irmgard U. Haussmann, Liao HongZhi…·Matthias Soller
The paper identifies Srrm234 as a key regulator of Dscam exon 9 alternative splicing, showing that canonical SR and hnRNP proteins have minimal impact on this process.