A Conformation-specific Nanobody Targeting the NMN-activated State of SARM1
Yun Nan Hou, Yang Cai, Wan Hua Li, Wei Ming He, Zhi Ying Zhao, Wen Jie Zhu, Qiang Wang, Jun Liu, Hon Cheung Lee, Goran Stjepanović, Hongmin Zhang, Yong Juan Zhao
The paper develops a nanobody that specifically targets the NMN-activated state of SARM1, enabling structural analysis and functional studies of this conformation.
bioRxiv · Mar 25, 2022 · PreprintMolecular Biology