Structural basis of nucleosomal H4K20 recognition and methylation by SUV420H1 methyltransferase
Fo-lan Lin, Ruxin Zhang, Weihan Shao, Cong Lei, Mingxi Ma, Ying Zhang, Zengqi Wen, Wanqiu Li
This study reveals the structural basis of SUV420H1's recognition and methylation of H4K20 on nucleosomes, showing how H2A.Z enhances its catalytic activity and how mutations affect its function.
Cell Discovery · Dec 5, 2023Peer-reviewedMolecular Biology