Induction of Autophagy Prevents Mutant SOD1G93A Related Neurotoxicity in Experimental Models of Amyotrophic Lateral Sclerosis (ALS)
Yue Bi, Xin Yan, Nazmiye Yacipi, Weisong Duan, Chunyan Li, Martin J. Thompson, Zhiying Jenny Shan, Lanrong Bi
This study investigates the therapeutic potential of IADB in ALS models, showing it promotes autophagy and reduces mutant SOD1 aggregates, oxidative stress, and disease progression.
bioRxiv · Nov 2, 2022 · PreprintNeuroscience