Selenoprotein P Deficiency Drives Hepatocellular Carcinoma Progression via Induction of Neutrophil Senescence and Immunosuppressive Microenvironment
Jiazheng Jiao, Lele Song, Shengjun Xu, Yuan Xue, Yanyan Liao, Keying Xu, Qian Wen, Kai Xiang, Rongrong Chen, Xiaoxia Dong, Weiwei Ji, Yinlong Guo, Gang Li, Haibiao Bao, Xiao Xu, Lixing Zhan
This study shows that selenoprotein P deficiency promotes hepatocellular carcinoma by inducing neutrophil senescence and an immunosuppressive microenvironment.
Gut · Apr 1, 2026Peer-reviewedCancer Biology