Atlas of genetic effects in human microglia transcriptome across brain regions, aging and disease pathologies
Kátia de Paiva Lopes, Gijsje J. L. Snijders, Jack Humphrey, Amanda Allan, Marjolein A. M. Sneeboer, Elisa Navarro, Brian M. Schilder, Ricardo A. Vialle, Madison Parks, Roy D. Missall, Welmoed van Zuiden, Frederieke A. J. Gigase, Raphael Kübler, Amber Berdenis van Berlekom, Emily M. Hicks, , Towfique Raj
The paper analyzes the transcriptome of human microglia across brain regions, aging, and disease to identify genetic effects on gene expression and splicing, linking them to neurological disorders.
Nature Genetics · Jan 1, 2022Peer-reviewedGenetics