Raphael Kübler

The paper identifies microglial states associated with Parkinson's disease genetic risk and Lewy body pathology using single-cell profiling and integrates data with AMP PD.

The paper quantifies HIV persistence in microglia and shows transcriptional changes in microglia and other cell types despite ART, highlighting microglia as a key target for CNS HIV cure strategies.

The paper characterizes the human microglia responsome by analyzing gene expression in microglia exposed to various stimuli, identifying distinct responses and genetic interactions relevant to disease.

This paper introduces a cerebral organoid model with integrated microglia to study how inflammatory stimuli and microglial presence affect neurodevelopment and neurodevelopmental disorders.

The paper analyzes the transcriptome of human microglia across brain regions, aging, and disease to identify genetic effects on gene expression and splicing, linking them to neurological disorders.