Author

Wen-Hsuan Wu

Columbia University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1

Frequent Co-Authors

Aykut DemirkoliD· 2 shared Georgy Komissarov· 2 shared Stephen H. TsangiD· 2 shared Thomas WinogrodzkiiD· 2 shared Anders Knudsen· 1 shared Anders Steen KnudseniD· 1 shared Angela ArmentoiD· 1 shared Bernd WissingeriD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersImmunology

Aykut DemirkolORCID

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2 papers

Recent·Most cited

A synthetic PGC1α co-activator reprograms microglial immunometabolism to preserve cone function in retinal degeneration

Thomas Winogrodzki, Jayvin Hernandez-Reyes, Rajvir Mukesh Solanky, Richard Lowery, Georgy Komissarov, Wen Huang, Boyuan Wang, Neoklis Makrides, Sharifa Davis, Siyuan Liu, Yong-Shi Li, Wen-Hsuan Wu, Nicholas Nolan, Robert P. van de Werken, Aykut Demirkol, , Stephen H. Tsang

bioRxiv · Oct 5, 2026 · PreprintImmunology

A mutation-agnostic and allele-specific ASO strategy demonstrates potent functional rescue and retinal preservation in RHO-linked retinitis pigmentosa

Salome Spaag, Wen-Hsuan Wu, Justin Yun, Aykut Demirkol, Thomas Winogrodzki, Anders Steen Knudsen, Georgy Komissarov, Chyuan‐Sheng Lin, Melita Kaltak, Maddalena Fuso, Kaushambee J Dave, Katarína Štingl, Angela Armento, Laura Kuehlewein, Britta Baumann, , Pietro De Angeli

This paper develops an allele-specific ASO strategy, SNARE, that selectively suppresses mutant RHO transcripts in RHO-linked retinitis pigmentosa, demonstrating functional rescue and retinal preservation in both in vitro and in vivo models.

bioRxiv · Sep 1, 2026 · PreprintGenetics