Author

Wenzheng Zhang

University of Colorado AnschutzPrimary ORCID profile (0000-0002-8771-0747 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Wenzheng ZhangiD1 paper · Albany Medical College

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Brian Kosmyna· 1 shared Christopher R. TrottaiD· 1 shared Jairo Sierra· 1 shared Jingxin WangiD· 1 shared Joseph A. GiovinazzoiD· 1 shared Karoline A. LambertiD· 1 shared Kerstin A. Effenberger· 1 shared Lanqing Ying· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Brian Kosmyna

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1 paper

Recent·Most cited

The U1 snRNP protein U1C and Helix H of U1 snRNA are critical for small molecule splicing modulator function

Zhiling Kuang, Brian Kosmyna, Xueni Li, Zhichao Tang, Shasha Shi, Karoline A. Lambert, Wenzheng Zhang, Joseph A. Giovinazzo, Kerstin A. Effenberger, Jairo Sierra, Lanqing Ying, Scott J. Barraza, Wencheng Li, Jingxin Wang, Christopher R. Trotta, Rui Zhao

This study shows that U1C and Helix H of U1 snRNA are essential for branaplam's effect on weak 5 splice site recognition, while risdiplam requires additional factors for activity.

Nature Communications · Jul 16, 2026Peer-reviewedBiochemistry