Retroviral insertions contributed to the divergence of human and chimpanzee brains
Patricia Gerdes, Ofelia Karlsson, Raquel Garza, Diahann A. M. Atacho, PingHsun Hsieh, Bharat Prajapati, Chandramouli Muralidharan, Anita Adami, Carrie Davis-Hansson, Emily M. Johansson, Laura Castilla‐Vallmanya, Wiktor West, Meghna Vinod, Lucian Domitrovic, Pia Annette Johansson, , Johan Jakobsson
This study identifies a chimpanzee-specific retroviral insertion that influences gene regulation and brain development, highlighting its role in human-chimpanzee brain divergence.
bioRxiv · Dec 12, 2025 · PreprintEvolutionary Biology