Structure of full-length APOBEC3B bound to EBV BORF2 reveals coordinated neutralization of a cancer-associated mutator
William Fried, Ziyuan Li, Connor Qiu, Lindsey Whalen, Hanjing Yang, Xiaojiang S. Chen
This study determines the structure of full-length APOBEC3B bound to EBV BORF2, showing how the NTD and CTD domains coordinate to neutralize A3B's mutagenic activity.
bioRxiv · Jun 19, 2026 · PreprintCancer Biology