Hanjing Yang

This study identifies APOBEC3G splicing defects in nonhuman primates that lead to different viral mutation profiles compared to humans.

This study determines the structure of full-length APOBEC3B bound to EBV BORF2, showing how the NTD and CTD domains coordinate to neutralize A3B's mutagenic activity.

This study identifies how AA/GA dinucleotides downstream of target-C sites enhance APOBEC3G DNA editing through structural and biochemical analysis of rhesus macaque A3G.

This study presents cryoEM structures of SARS-CoV-2 Nsp15 bound to dsRNA, revealing how it recognizes and cleaves poly(U) tracts to evade host immunity.