Author

William J. Buscher

Washington University in St. Louis

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Neuroscience· 1

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Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Albert A. DavisiD· 1 shared Conrad Chris WeihliD· 1 shared Dhruva D. DhavaleiD· 1 shared Jan BieschkeiD· 1 shared Jessica N. Patterson· 1 shared Jiang ZhuiD· 1 shared Mohamed Salman Kaleelurrrahuman· 1 shared Paul T. KotzbaueriD· 1 shared

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2021-2021 · peak 1/yr

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1 shared paperNeuroscience

Albert A. DavisORCID

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1 paper

Recent·Most cited

VCP protects neurons from proteopathic seeding

Jiang Zhu, Sara K. Pittman, Dhruva D. Dhavale, Rachel L. French, Jessica N. Patterson, Mohamed Salman Kaleelurrrahuman, Yuanzi Sun, William J. Buscher, Jan Bieschke, Paul T. Kotzbauer, Yuna M. Ayala, Albert A. Davis, Conrad Chris Weihl

This study identifies VCP as a suppressor of proteopathic seeding and shows that VCP dysfunction increases seeding of multiple aggregates, contributing to neurodegeneration.

bioRxiv · Jul 12, 2021 · PreprintNeuroscience