Author

Jan Bieschke

MRC Prion UnitORCID 0000-0002-3485-9767Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:long-read sequencing· 1 Approach:statistical model· 1

Frequent Co-Authors

Albert A. DavisiD· 1 shared Anna‐Leigh BrowniD· 1 shared Conrad Chris WeihliD· 1 shared Dhruva D. DhavaleiD· 1 shared Elisa M. CrombieiD· 1 shared Elizabeth FisheriD· 1 shared Jessica N. Patterson· 1 shared Jiang ZhuiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Albert A. DavisORCID

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2 papers

Recent·Most cited

Taf1 expression in mouse: novel transcripts and protein distribution

Peihang Li, Karen Cleverley, Elisa M. Crombie, Jan Bieschke, Elizabeth Fisher, Anna‐Leigh Brown

The paper identifies novel Taf1 transcripts and protein distribution in mouse, revealing transcriptional diversity and elevated expression in cerebellum.

bioRxiv · Sep 8, 2025 · PreprintBioinformatics

VCP protects neurons from proteopathic seeding

Jiang Zhu, Sara K. Pittman, Dhruva D. Dhavale, Rachel L. French, Jessica N. Patterson, Mohamed Salman Kaleelurrrahuman, Yuanzi Sun, William J. Buscher, Jan Bieschke, Paul T. Kotzbauer, Yuna M. Ayala, Albert A. Davis, Conrad Chris Weihl

This study identifies VCP as a suppressor of proteopathic seeding and shows that VCP dysfunction increases seeding of multiple aggregates, contributing to neurodegeneration.

bioRxiv · Jul 12, 2021 · PreprintNeuroscience