Community assembly modeling of microbial evolution within Barrett's esophagus and esophageal adenocarcinoma
Caitlin Guccione, I. Sfiligoi, Antonio Gonzalez, Justin P. Shaffer, Mariya Kazachkova, Yuhan Weng, Daniel McDonald, Shailja C. Shah, Samuel S. Minot, Thomas G. Paulson, William M. Grady, Ludmil B. Alexandrov, Rob D. Knight, Kit Curtius
The paper models microbial community assembly dynamics in Barrett's esophagus and esophageal adenocarcinoma, finding neutral dynamics in normal tissue and BE but not EAC, with H. pylori showing non-neutral behavior in BE non-cancer outcomes.
BMC Genomics · Feb 10, 2026Peer-reviewedCancer Biology