Kit Curtius

The paper models microbial community assembly dynamics in Barrett's esophagus and esophageal adenocarcinoma, finding neutral dynamics in normal tissue and BE but not EAC, with H. pylori showing non-neutral behavior in BE non-cancer outcomes.

CNETML infers phylogenies from spatio-temporal copy number profiles of cancer samples, handling total copy numbers and temporal data to estimate mutation rates and tree topology.

This paper identifies mutational signatures caused by formalin fixation and introduces FFPEsig, a method to correct these artefacts in genome sequencing data.