A molecular switch for stress-induced activation of retrograde mitochondrial transport
Christina Gladkova, Maria G Paez-Segala, William P Grant, Samuel A. Myers, Yuxiao Wang, Ronald D. Vale
The paper identifies a regulatory helix in TRAK that mediates switching between kinesin- and dynein-driven mitochondrial transport in response to stress.
bioRxiv · Sep 13, 2024 · PreprintMolecular Biology