Molecular insights into the gating mechanisms of voltage-gated calcium channel CaV2.3
Y. Gao, S. Xu, X. Cui, H. Xu, Y. Qiu, Y. Wei, Y. Dong, B. Zhu, C. Peng, S. Liu, X. C. Zhang, J. Sun, Z. Huang, Y. Zhao
This study determines the cryo-EM structure of human CaV2.3 channels and identifies key residues and interactions involved in channel gating and inactivation.
bioRxiv · Dec 19, 2022Biophysics